Week 6 of the college football schedule is here, and now it time to make our final picks and predictions for Saturday most important games.There are three matchups on tap featuring AP top 25 ranked teams on the same field, including one surprise game in the Big 12, in addition to one in the SEC, and an intriguing kickoff coming out of the Pac-12.More college football on SI: College football scores | College football rankings | College football scheduleThis week also finds the annual Red River Shootout from the Cotton Bowl pitting Texas and Oklahoma, although the old rivals are down this year, both unranked and at 3-2 coming in.And there a major tilt down in the SEC as top-ranked Alabama plays host to Texas AM in a rematch of last season major upset and the Aggies looking to avoid a costly third loss on the year.Here are the final picks from the gang on ESPN College GameDay.College football predictions: ESPN College Game Day makes final Week 6 game picksWeek 6 college football picks, predictionsTexas vs. Oklahoma. All but one host went with the Longhorns Will Brooks Jersey, who return quarterback Quinn Ewers to throw against an ailing Sooner secondary in the Red River Shootout.College Football HQ pick: Texas by 16Iowa at Illinois. All four analysts siding with the Illini in the Big Ten game up against a stout Hawkeye defense, but an air attack that still hasnt found its footing. College Football HQ pick: Illinois by 6BYU vs. Notre Dame. An even split between these teams, with BYU coming in ranked at one loss but the unranked 2-2 Irish the slim favorite at the books.